Abstract | INTRODUCTION: METHODS: Sixty MG patients with blepharoptosis (32 with ocular symptoms only and 28 with mild generalized symptoms) were enrolled in a multicenter open trial of topical naphazoline. The effects were reported by patients via a questionnaire and were also confirmed for each patient at the clinic. RESULTS: Among 70 eyes of 60 patients, 20 eyes (28.6%) of 17 patients (28.3%) exhibited a marked response (full eye opening), and 24 eyes (34.3%) of 20 patients (33.3%) showed a good response (adequate but incomplete eye opening). Topical naphazoline was evaluated as useful in the treatment of myasthenic blepharoptosis by >70% of the patients. CONCLUSIONS:
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Authors | Yuriko Nagane, Kimiaki Utsugisawa, Shigeaki Suzuki, Masayuki Masuda, Yuko Shimizu, Hiroya Utsumi, Shinichiro Uchiyama, Norihiro Suzuki |
Journal | Muscle & nerve
(Muscle Nerve)
Vol. 44
Issue 1
Pg. 41-4
(Jul 2011)
ISSN: 1097-4598 [Electronic] United States |
PMID | 21491460
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Multicenter Study)
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Copyright | Copyright © 2011 Wiley Periodicals, Inc. |
Chemical References |
- Pharmaceutical Solutions
- Naphazoline
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Topics |
- Administration, Topical
- Adult
- Aged
- Blepharoptosis
(complications, drug therapy)
- Female
- Humans
- Male
- Middle Aged
- Myasthenia Gravis
(complications, drug therapy)
- Naphazoline
(administration & dosage)
- Pharmaceutical Solutions
(administration & dosage)
- Treatment Outcome
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