[Acute bacterial salpingitis. The importance of residual inflammation. A comparative study with celioscopic control of 2 antibiotic protocols: sulbactam-ampicillin versus cefoxitin].

Abstract

The combination of sulbactam-ampicillin was compared to cefoxitin for the treatment of acute salpingitis in 40 women divided into two groups of 20 women each. There were 11 patients in each group who were given doxycycline because of evidence of chlamydial infection. All patients were diagnosed by laparoscopic examination and evaluated by the same procedure 7-12 weeks later: At the second laparoscopy, only 1 of the 20 patients (5%) treated with sulbactam/ampicillin had severe adhesions, while 6 of the 20 patients (40%) treated with cefoxitin had severe adhesions. Tubal patency was without obstruction in 14 patients (70%) given the combination treatment and in 12 patients (60%) given cefoxitin. Side effects were essentially absent in both groups.

• Authors: G Le Bouedec, J L Pouly, G Mage, M Canis, A Wattiez, B Abbas Muhktar, M A Bruhat
• Journal: Journal de gynecologie, obstetrique et biologie de la reproduction (J Gynecol Obstet Biol Reprod (Paris)) Vol. 19 Issue 6 Pg. 765-72 ( 1990) ISSN: 0368-2315 [Print] France
• Vernacular Title: Salpingites aiguës bactériennes. Importance de l'inflammation résiduelle. Etude comparative avec contrôle coelioscopique de 2 protocoles antibiotiques: sulbactam-ampicilline versus céfoxitine.
• PMID: 2147930 (Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, English Abstract, Journal Article)

Chemical References

• Cefoxitin
• Ampicillin
• Sulbactam

Topics

• Adult
• Ampicillin (administration & dosage, therapeutic use)
• Bacterial Infections (diagnosis, drug therapy, pathology)
• Cefoxitin (administration & dosage, therapeutic use)
• Drug Therapy, Combination
• Evaluation Studies as Topic
• Female
• Humans
• Laparoscopy (standards)
• Prognosis
• Salpingitis (diagnosis, drug therapy, pathology)
• Sulbactam (administration & dosage, therapeutic use)