A controlled trial of clobetasol propionate ointment 0.05% in the treatment of experimentally induced Rhus dermatitis.

Abstract

We studied the effectiveness of clobetasol propionate ointment 0.05% in experimentally induced Rhus dermatitis. Clobetasol rapidly decreased the vesiculation at each treated site, although the effect was most prominent at the site to which clobetasol was applied the earliest, that is, at 12 hours after exposure to Rhus extract. On the basis of this experimental model, clobetasol propionate ointment 0.05% may be effective therapy for naturally occurring Rhus dermatitis.

• Authors: H J Vernon, E A Olsen
• Journal: Journal of the American Academy of Dermatology (J Am Acad Dermatol) Vol. 23 Issue 5 Pt 1 Pg. 829-32 (Nov 1990) ISSN: 0190-9622 [Print] United States
• PMID: 2147698 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Ointments
• Clobetasol

Topics

• Adult
• Clobetasol (administration & dosage, analogs & derivatives, therapeutic use)
• Dermatitis, Toxicodendron (drug therapy, etiology)
• Edema (drug therapy, etiology)
• Erythema (drug therapy, etiology)
• Female
• Humans
• Male
• Ointments
• Skin Tests