Abstract |
A 38-year-old man with complaints of nausea, epigastralgia, cough, and decrease body weight was given a diagnosis of advanced gastric cancer (type 4) with carcinomatous lymphangitis of the lung (UM-circ cT3, N3, H0, P0, M1, stage IV, por2). He was treated with combination of docetaxel (DOC) 40 mg/m(2)/day (days 1, 15) and S-1 orally 80 mg/m(2)/day (days 1-7, 15-21), 1 week administered 1 week rest. After 2 courses of treatment, the patient achieved a partial response in the carcinomatous lymphangitis of the lung. Tumor markers decreased and symptoms improved. He experienced grade 2 peripheral neuropathy but with no grade 3 adverse events. Although the prognosis of gastric cancer with carcinomatous lymphangitis is poor. These results indicate that bi-weekly DOC and S-1 combination chemotherapy might be effective for gastric cancer with carcinomatous lymphangitis of the lung.
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Authors | Yumi Daimon, Masazumi Takahashi, Taichi Yabuno, Jun Watanabe, Yasuhisa Mochizuki, Fumihiko Kito, Sachiko Yoshida |
Journal | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
(Nihon Shokakibyo Gakkai Zasshi)
Vol. 108
Issue 4
Pg. 605-10
(Apr 2011)
ISSN: 0446-6586 [Print] Japan |
PMID | 21467767
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Antimetabolites, Antineoplastic
- Antineoplastic Agents
- Drug Combinations
- Taxoids
- S 1 (combination)
- Tegafur
- Docetaxel
- Oxonic Acid
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Topics |
- Adenocarcinoma
(drug therapy)
- Adult
- Antimetabolites, Antineoplastic
(administration & dosage)
- Antineoplastic Agents
(administration & dosage)
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Docetaxel
- Drug Combinations
- Humans
- Lung Neoplasms
(drug therapy)
- Lymphangitis
(drug therapy)
- Male
- Oxonic Acid
(administration & dosage)
- Stomach Neoplasms
(drug therapy)
- Taxoids
(administration & dosage)
- Tegafur
(administration & dosage)
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