Keloid formation after syndactyly release in patients with associated macrodactyly: management with methotrexate therapy.

Abstract

We present a series of cases of keloid formation after release of syndactyly in the hands and feet of children with associated digital overgrowth. The use of methotrexate to suppress keloid formation after release of syndactyly and for control of recurrence after surgery for keloid is effective.

• Authors: S K Tolerton, M A Tonkin
• Journal: The Journal of hand surgery, European volume (J Hand Surg Eur Vol) Vol. 36 Issue 6 Pg. 490-7 (Jul 2011) ISSN: 2043-6289 [Electronic] England
• PMID: 21447529 (Publication Type: Case Reports, Journal Article)

Chemical References

• Dermatologic Agents
• Folic Acid
• Methotrexate

Topics

• Adolescent
• Child
• Child, Preschool
• Compression Bandages
• Dermatologic Agents (therapeutic use)
• Drug Therapy, Combination
• Female
• Fingers (abnormalities, surgery)
• Folic Acid (therapeutic use)
• Follow-Up Studies
• Foot Deformities, Congenital (surgery)
• Hand Deformities, Congenital (surgery)
• Humans
• Infant
• Infant, Newborn
• Keloid (drug therapy)
• Male
• Methotrexate (therapeutic use)
• Postoperative Care (methods)
• Postoperative Complications (drug therapy, surgery)
• Reoperation
• Secondary Prevention
• Syndactyly (surgery)
• Toes (abnormalities, surgery)