Surviving stiff-person syndrome: a case report.

Abstract

Stiff-person syndrome (SPS) is a rare condition of progressive muscular rigidity and spasm, frequently accompanied by other autoimmune conditions, an association which has been further strengthened by the discovery of anti-GAD antibodies and the response of SPS to immunotherapies. Intravenous immunoglobulin (IVIg) is the mainstay therapy. Because of the rarity of the GAD antibody associated conditions, most of the information regarding treatment is case series and individual case reports. Here we describe the 15 year long management of a subject with SPS who has had a favourable outcome.

• Authors: Sharmilee Gnanapavan, Angela Vincent, Gavin Giovannoni
• Journal: Journal of neurology (J Neurol) Vol. 258 Issue 10 Pg. 1898-900 (Oct 2011) ISSN: 1432-1459 [Electronic] Germany
• PMID: 21442460 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Immunoglobulins, Intravenous
• Immunosuppressive Agents

Topics

• Humans
• Immunoglobulins, Intravenous (therapeutic use)
• Immunosuppressive Agents (therapeutic use)
• Male
• Middle Aged
• Stiff-Person Syndrome (drug therapy)