Abstract |
Thirty seven strains of Escherichia coli isolated from the urine of patients with acute symptomatic urinary tract infection were examined for siderophore production: hydroxamate ( aerobactin) and phenolate ( enterochelin). All the strains were found to produce varying amounts of enterochelin. With the chemical assay, 24.3% strains were aerobactin producers, while 43.2% were positive in the bio-assay. All the aerobactin producers carried the aerobactin receptor on their surface. Attempts to correlate siderophore production with growth in minimal and iron-depleted medium showed that there was a positive quantitative correlation between enterochelin production and growth of organisms under iron depletion. Aerobactin production failed to give an additional advantage of growth to strains producing enterochelin.
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Authors | K Harjai, M Saxena, S Chhibber, S Sharma |
Journal | Folia microbiologica
(Folia Microbiol (Praha))
Vol. 35
Issue 2
Pg. 149-54
( 1990)
ISSN: 0015-5632 [Print] United States |
PMID | 2143166
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
- Bacterial Outer Membrane Proteins
- Hydroxamic Acids
- Iron Chelating Agents
- Receptors, Immunologic
- Siderophores
- aerobactin receptor
- aerobactin
- Enterobactin
- Serine
- Iron
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Topics |
- Bacterial Outer Membrane Proteins
- Enterobactin
(metabolism)
- Escherichia coli
(drug effects, growth & development, isolation & purification)
- Escherichia coli Infections
(microbiology)
- Humans
- Hydroxamic Acids
(metabolism)
- Iron
(metabolism, pharmacology)
- Iron Chelating Agents
(metabolism)
- Receptors, Immunologic
(analysis)
- Serine
(analogs & derivatives)
- Siderophores
- Urinary Tract Infections
(microbiology)
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