[Activity of ectoenzymes of the heart breaking up ATP in the period of myocardial reperfusion after ischemia].

Abstract

Nowadays the activity of heart ectoenzymes, breaking up ATP, are determined in the undamaged tissue to eliminate the effect to the ATP of intracellular enzymes. Our aim is to study the activity of ecto-adenosine triphosphatase in the heart damaged by ischemia. It was established that the activity of ectoenzymes, breaking up ATP, may be measured in the tissue damaged by ischemia only in case when the cellular membrane becomes impermeable for the intracellular enzymes. The activity of adenosine triphosphatase is significantly reduced during the myocardial reperfusion after ischemia and appeared as one of the criteria by which we can assume the degree of the heart reperfusion damage.

• Authors: V V Alabovskiĭ, O D Oleĭnikov, V V Riabova
• Journal: Biulleten' eksperimental'noi biologii i meditsiny (Biull Eksp Biol Med) Vol. 109 Issue 5 Pg. 436-8 (May 1990) ISSN: 0365-9615 [Print] Russia (Federation)
• Vernacular Title: Aktivnost' éktofermentov serdtsa, rasshchepliaiushchikh ATF, v period reperfuziĭ miokarda posle ishemii.
• PMID: 2143089 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Adenosine Triphosphate
• Adenosine Triphosphatases

Topics

• Adenosine Triphosphatases (metabolism)
• Adenosine Triphosphate (metabolism)
• Animals
• Cell Membrane (enzymology)
• Heart (physiopathology)
• In Vitro Techniques
• Ischemia (physiopathology)
• Myocardial Contraction
• Myocardial Reperfusion Injury (enzymology, etiology, physiopathology)
• Myocardium (enzymology, metabolism)
• Rats