Abstract | BACKGROUND/AIMS: METHODS: Debate transcripts, debaters' and discussants' reviews and literature citations were the basis of this report. RESULTS: Participants agreed that saturates per se are not 'bad', but that dietary recommendations should emphasize the substitution of unsaturates for part of the saturates. Evidence supporting omega-6 PUFA intakes of 5 to 10% is mixed; some interpret the overall data from diverse studies as consistent with a reduction in the risk of cardiovascular mortality and events. Others assert that randomized controlled trial data suggest that higher intakes of omega-6 PUFAs are not associated with lower risk of heart disease, or may even increase it. CONCLUSIONS: All agreed that a 5-year randomized controlled trial comparing the effects of historically low (2%) with currently high (7.5%) linoleic acid intakes on cardiac endpoints would address the knowledge gap about the effects of different omega-6 PUFA intakes on the risk of heart disease.
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Authors | Joyce A Nettleton, Berthold Koletzko, Gerard Hornstra |
Journal | Annals of nutrition & metabolism
(Ann Nutr Metab)
Vol. 58
Issue 1
Pg. 59-65
( 2011)
ISSN: 1421-9697 [Electronic] Switzerland |
PMID | 21430375
(Publication Type: Journal Article)
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Copyright | Copyright © 2011 S. Karger AG, Basel. |
Chemical References |
- Fatty Acids, Omega-3
- Fatty Acids, Omega-6
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Topics |
- Congresses as Topic
- Diet
- Fatty Acids, Omega-3
(administration & dosage)
- Fatty Acids, Omega-6
(administration & dosage)
- Heart Diseases
(prevention & control)
- Humans
- Randomized Controlled Trials as Topic
- Risk Factors
|