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[Folinic acid in the treatment of elderly patients with macrocytic anemia].

Abstract
Thirty elderly patients suffering from macrocytic anaemia associated with chronic diseases were treated with folinic acid for 25 days at a dosage of 4-8 mg daily. For each patient routine laboratory tests have been carried out, the clinical parameters have been recorded at the beginning and at the end of the trial and after 8 days of treatment a possible reticulocyte crisis has been evaluated. The results showed a significant decrease of medium corpuscular volume (MCV), of mean corpuscular haemoglobin (MCH), of iron as well as an increase of folic acid in the serum. After 8 days of treatment a statistically significant reticulocyte crisis was observed.
AuthorsR Lucchi, A Criserà, M G Ferrari, A C Sacchetta
JournalLa Clinica terapeutica (Clin Ter) Vol. 133 Issue 3 Pg. 159-63 (May 15 1990) ISSN: 0009-9074 [Print] Italy
Vernacular TitleL'acido folinico come terapia in pazienti anziani portatori di anemia macrocitica.
PMID2142903 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Leucovorin
Topics
  • Aged
  • Aged, 80 and over
  • Anemia, Macrocytic (drug therapy)
  • Drug Evaluation
  • Female
  • Humans
  • Leucovorin (therapeutic use)
  • Male
  • Middle Aged

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