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How MRI can contribute to the diagnosis of acute demyelinating encephalomyelitis in children.

AbstractOBJECTIVE:
To illustrate through 10 pediatric cases, the clinical features, course, and importance of neuroimaging (especially MRI) in guiding the diagnosis of acute disseminated encephalomyelitis (ADEM) and controlling patients after treatment.
METHODS:
A retrospective review of 10 pediatric cases of ADEM, with special regard to the MRI features, presenting to the Pediatric Departments, Hedi Chaker Hospital, Sfax, Tunisia between January 2002 and December 2008.
RESULTS:
Children with ADEM presented with variable and multiple neurological signs most often occurring after an infectious episode, especially after upper respiratory tract infection. The MRI permitted confirmation of the diagnosis by showing demyelinating lesions either in the brainstem, the cerebellum, the cerebral white and grey matter, or in the spine of all patients.
CONCLUSION:
Acute disseminated encephalomyelitis is characterized by multifocal demyelinating lesions resulting in varied neurological signs. The MRI is the technique of choice to show these lesions.
AuthorsEmna Daoud, Imen Chabchoub, Henda Neji, Nozha Toumi, Rim B Abdallah, Hajer Aloulou, Fatma Kammoun, Abdelmajid Mahfoudh, Mongia Hachicha, Jamel Mnif, Kheireddine B Mahfoudh, Zeineb Mnif
JournalNeurosciences (Riyadh, Saudi Arabia) (Neurosciences (Riyadh)) Vol. 16 Issue 2 Pg. 137-45 (Apr 2011) ISSN: 1319-6138 [Print] Saudi Arabia
PMID21427663 (Publication Type: Journal Article)
Chemical References
  • Adrenal Cortex Hormones
  • Antiviral Agents
  • Acyclovir
Topics
  • Acyclovir (therapeutic use)
  • Adolescent
  • Adrenal Cortex Hormones (therapeutic use)
  • Antiviral Agents (therapeutic use)
  • Child
  • Child, Preschool
  • Encephalomyelitis, Acute Disseminated (diagnosis, therapy)
  • Female
  • Humans
  • Infant
  • Magnetic Resonance Imaging (methods)
  • Male
  • Retrospective Studies
  • Treatment Outcome

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