Abstract | INTRODUCTION AND HYPOTHESIS: This study describes the incidence, risk factors, and treatments of graft erosion, wound granulation, and dyspareunia as adverse events following vaginal repair of pelvic organ prolapse with non-absorbable synthetic and biologic graft materials. METHODS: A systematic review in Medline of reports published between 1950 and November 2010 on adverse events after vaginal prolapse repairs using graft materials was carried out. RESULTS: One hundred ten studies reported on erosions with an overall rate, by meta-analysis, of 10.3%, (95% CI, 9.7 - 10.9%; range, 0 - 29.7%; synthetic, 10.3%; biological, 10.1%). Sixteen studies reported on wound granulation for a rate of 7.8%, (95% CI, 6.4 - 9.5%; range, 0 - 19.1%; synthetic, 6.8%; biological, 9.1%). Dyspareunia was described in 70 studies for a rate of 9.1%, (95% CI, 8.2 - 10.0%; range, 0 - 66.7%; synthetic, 8.9%; biological, 9.6%). CONCLUSIONS:
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Authors | Husam Abed, David D Rahn, Lior Lowenstein, Ethan M Balk, Jeffrey L Clemons, Rebecca G Rogers, Systematic Review Group of the Society of Gynecologic Surgeons |
Journal | International urogynecology journal
(Int Urogynecol J)
Vol. 22
Issue 7
Pg. 789-98
(Jul 2011)
ISSN: 1433-3023 [Electronic] England |
PMID | 21424785
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review, Systematic Review)
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Topics |
- Dyspareunia
(epidemiology, etiology)
- Female
- Granulation Tissue
- Humans
- Incidence
- Pelvic Organ Prolapse
(surgery)
- Postoperative Complications
(epidemiology, etiology, therapy)
- Surgical Mesh
(adverse effects)
- Vagina
(surgery)
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