Enucleation and liquid nitrogen cryotherapy in the treatment of keratocystic odontogenic tumors: a case series.

Abstract

PURPOSE:

This study describes the technique of lesion enucleation without capsule disruption combined with liquid nitrogen cryotherapy in the surgical treatment of keratocystic odontogenic tumors (KOTs).

PATIENTS AND METHODS:

Eight patients (9 KOTs) were included in the study. After enucleation, liquid nitrogen was applied twice for 1 minute, with 5-minute intervals between applications. The patients were followed up for 3 to 9 years.

RESULTS:

There were no recurrences during the follow-up of 9 KOTs for up to 9 years. Only 1 patient had temporary reversible loss of lip sensation after treatment. There were no pathologic fractures. In all cases bone height at the surgical site was restored, and no patients needed bone reconstruction for post-treatment rehabilitation.

CONCLUSIONS:

This study confirmed the efficiency of KOT treatment enucleation without fragmentation combined with liquid nitrogen cryotherapy at the surgical site.

• Authors: Leonardo Tonietto, Hedelson Odenir Iecher Borges, Carlos Alberto Medeiros Martins, Daniela Nascimento Silva, Manoel Sant'Ana Filho
• Journal: Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons (J Oral Maxillofac Surg) Vol. 69 Issue 6 Pg. e112-7 (Jun 2011) ISSN: 1531-5053 [Electronic] United States
• PMID: 21419550 (Publication Type: Journal Article)
• Copyright: Copyright © 2011 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

Chemical References

• Nitrogen

Topics

• Adolescent
• Adult
• Child
• Combined Modality Therapy
• Cryotherapy
• Female
• Humans
• Male
• Mandibular Diseases (surgery, therapy)
• Mandibular Neoplasms (surgery, therapy)
• Nitrogen (administration & dosage)
• Odontogenic Cysts (surgery, therapy)
• Odontogenic Tumors (surgery, therapy)
• Young Adult