Glutathione peroxidase (GSHPx) activity in the liver of red deer in relation to hepatic selenium concentrations, sex, body weight and season of the year.
|
| Abstract |
The purpose of this study was to determine glutathione peroxidase (GSHPx) activity in the liver of red deer in relation to selenium concentrations in the liver, as well as to evaluate changes in GSHPx activity according to sex, body weight and season of the year. Total selenium concentration in the liver of red deer averaged 0.095 ± 0.018 μg/g of wet weight. GSHPx activity in the liver of red deer ranged widely from 4.4 to 45.8 U/g of protein. Females were characterized by higher GSHPx activity compared to males (21.2 vs. 17.0 U/g protein). The highest GSHPx activity was recorded in autumn and the lowest in summer. The lowest GSHPx activity in the liver was found in the heaviest animals (>100 kg body weight), averaging 14.0 U/g protein. Animals weighing <66 kg and 66-100 kg were characterized by similar activity of 25.1 and 24.5 U/g, respectively. Despite the differences in GSHPx activity according to sex, body weight and season of the year, these factors had no significant effect on the activity of this enzyme. The main factor regulating GSHPx activity in the liver of examined red deer was selenium concentration.
|
|---|---|
| Authors | Bogumiła Pilarczyk, Radosław Drozd, Renata Pilarczyk, Agnieszka Tomza-Marciniak, Dorota Jankowiak, Diana Hendzel, Jarosław Kuba, Joanna Kowalska |
| Journal | Biological trace element research (Biol Trace Elem Res) Vol. 144 Issue 1-3 Pg. 560-9 (Dec 2011) ISSN: 1559-0720 [Electronic] United States |
| PMID | 21416340 (Publication Type: Journal Article) |
| Chemical References |
|
| Topics |
|
Join CureHunter, for free Research Interface BASIC access!
Realize the full power of the drug-disease research graph!