Abstract | BACKGROUND AND PURPOSE: The purpose of this study was to investigate whether thyroid function and thyroid autoantibodies were associated with the risk of moyamoya disease in pediatric subjects. METHODS: RESULTS: We included 114 pediatric patients and 114 healthy control subjects. The patients displayed higher prevalence of increased thyroid function and elevated thyroid autoantibodies in comparison with control subjects. These remained significant after multivariate adjustment; the ORs (95% CI) for increased thyroid function and evaluated thyroid autoantibodies were evaluated as 12.47 (1.55 to 100.51) and 4.33 (1.29 to 14.59), respectively. CONCLUSIONS:
|
Authors | Hao Li, Zheng-Shan Zhang, Zhen-Nan Dong, Mai-Juan Ma, Wei-Zhong Yang, Cong Han, Ming-Mei Du, Yun-Xi Liu, Hong Yang, Wei Liu, Lian Duan, Wu-Chun Cao |
Journal | Stroke
(Stroke)
Vol. 42
Issue 4
Pg. 1138-9
(Apr 2011)
ISSN: 1524-4628 [Electronic] United States |
PMID | 21350209
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
|
Chemical References |
|
Topics |
- Adolescent
- Age Factors
- Autoantibodies
(biosynthesis, blood)
- Case-Control Studies
- Child
- Comorbidity
- Female
- Humans
- Hyperthyroidism
(complications, diagnosis, immunology)
- Male
- Moyamoya Disease
(complications, diagnosis, immunology)
- Prevalence
- Prospective Studies
- Risk Factors
- Thyroid Function Tests
- Thyroid Gland
(immunology, pathology)
- Up-Regulation
(immunology)
|