Jaw-opening dystonia: Quality of life after botulinum toxin injections.

Abstract

The objective of this study was to investigate quality-of-life outcomes in patients with jaw-opening oromandibular dystonia who had received treatment with botulinum neurotoxin injections. The Glasgow Benefit Inventory (GBI) was used as a post-intervention questionnaire to measure patient benefit. Twenty-five questionnaires were sent to patients. Of the 12 patients who returned the form (48% response rate), the mean scores for the general GBI subscore (p = 0.001), the social support GBI subscore (p = 0.031), and the physical health GBI subscore (p = 0.002) demonstrated statistically significant benefit from the injections. No scores demonstrated a negative impact. Botulinum neurotoxin injections were demonstrated to benefit the quality of life in patients suffering from jaw-opening oromandibular dystonia.

• Authors: Steven J Charous, Cynthia L Comella, Wenqing Fan
• Journal: Ear, nose, & throat journal (Ear Nose Throat J) Vol. 90 Issue 2 Pg. E9 (Feb 2011) ISSN: 1942-7522 [Electronic] United States
• PMID: 21328222 (Publication Type: Journal Article)

Chemical References

• Anti-Dyskinesia Agents
• Botulinum Toxins

Topics

• Adult
• Aged
• Anti-Dyskinesia Agents (therapeutic use)
• Botulinum Toxins (therapeutic use)
• Dystonia (drug therapy, psychology)
• Female
• Humans
• Male
• Mandibular Diseases (drug therapy, psychology)
• Middle Aged
• Quality of Life (psychology)
• Statistics, Nonparametric
• Surveys and Questionnaires
• Treatment Outcome