Abstract |
Twenty-nine patients of 18,000 inpatient admissions over a six-month period developed ischaemic hepatitis accompanied by peak aspartate aminotransferase (AST-EC 2.6.1.1) activity greater than 1,000 U/L. Seventeen of these 29 patients died either during or shortly after the episode of ischaemic hepatitis, with an overall mortality of 58.6%. Mortality was not due in any of the cases to the hepatitis but rather the underlying cause. Ischaemic hepatitis was the commonest cause of an AST activity greater than 1,000 U/L in this hospital population (29 of 52 patients i.e. 56%). This condition is more common than generally appreciated and is associated with a poor prognosis.
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Authors | P E Hickman, J M Potter |
Journal | Australian and New Zealand journal of medicine
(Aust N Z J Med)
Vol. 20
Issue 1
Pg. 32-4
(Feb 1990)
ISSN: 0004-8291 [Print] Australia |
PMID | 2132296
(Publication Type: Journal Article)
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Chemical References |
- Aspartate Aminotransferases
|
Topics |
- Aspartate Aminotransferases
(blood, physiology)
- Cardiac Output, Low
(complications)
- Cause of Death
- Hepatitis
(blood, etiology, mortality)
- Humans
- Ischemia
(blood, etiology, mortality)
- Liver
(blood supply)
- Prognosis
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