Occurrence of fat embolism after liposuction surgery with or without lipografting: an experimental study.

Abstract

BACKGROUND:

Liposuction in plastic surgery consists of the removal of excess fatty tissue in healthy individuals. In recent decades, this procedure has become more common worldwide. Associated with liposuction, lipografting has also been used for improving body contours, and has become known as liposculpture. Liposuction sometimes causes complications, including fat embolism, as described in the medical literature. The present study aims at ascertaining whether there is intravascular mobilization of fat after mechanical liposuction surgery and/or fat graft when carried out using one of the most common specific procedures used for liposuction, the superwet technique.

METHODS:

A total of 30 Wistar rats were included in this study. Before the surgery, the animals were placed in the supine position and anesthetized with thiopental for 50 to 60 minutes, as it is generally performed in clinical practice. The animals were divided in the following 3 groups. Group A, consisting of 10 rats, served as controls, and were only anesthetized. Group B consisted of 10 rats, which underwent only liposuction. Group C also comprised 10 rats, which were liposuctioned and then lipografted in the dorsal region. Blood was collected just before and again, 48 hours after the procedure. After 48 hours, the animals were killed, and the lungs, kidneys, liver, and brain were histologically examined.

RESULTS:

All the collected samples were analyzed microscopically with 2 different stains, namely, hematoxylin and eosin, and Sudan black. Fat particles were found in the lungs of 3 animals in group B (those that underwent only liposuction) and in 6 animals of group C (liposuction and lipografting). No fat particles were found in any organ of the control group.

CONCLUSIONS:

With this experiment, the authors showed that there is a risk of systemic mobilization of fat after liposuction surgery and that this risk is even higher when fat grafts are also carried out.

• Authors: Fernando F Franco, Alfio J Tincani, Luciana R Meirelles, Paulo Kharmandayan, Marcelo C Guidi
• Journal: Annals of plastic surgery (Ann Plast Surg) Vol. 67 Issue 2 Pg. 101-5 (Aug 2011) ISSN: 1536-3708 [Electronic] United States
• PMID: 21301303 (Publication Type: Journal Article)

Topics

• Adipose Tissue (transplantation)
• Animals
• Brain (pathology)
• Embolism, Fat (blood, etiology, pathology)
• Kidney (pathology)
• Lipectomy (adverse effects, methods)
• Liver (pathology)
• Lung (pathology)
• Male
• Rats
• Rats, Wistar