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Effectiveness of packed rice-oral rehydration solution among children with acute watery diarrhea.

AbstractOBJECTIVE:
This study aims to compare the effectiveness between the packed rice-oral rehydration solution (R-ORS) and the glucose-based oral rehydration solution (G-ORS) in children with acute watery diarrhea.
MATERIAL AND METHOD:
Randomized control trial was conducted to compare duration of diarrhea, stool frequency, incremental weight gain, intravenous fluid requirement, and duration of admission. Subjects were 70 pediatric patients (9-60 months-old) and were equally divided into two groups (n=35 for each): treatment group (with R-ORS treatment) and control group (with G-ORS treatment). The data were collected during January 1, 2007 to January 2008. All patients were treated with oral rehydration therapy within first 4 hours of admission. Intravenous rehydration was also scheduled. Both groups were fed with rice gruel or lactose-free formula as tolerated.
RESULTS:
Using survival analysis, both duration of diarrhea and admission was significantly shortened in the treatment group compared to the control group. (27.5 hrs. vs. 40.5 hrs: p = 0.01 and 40.1 hrs. vs. 56.0 hrs: p = 0.02 respectively). However, stool frequency, incremental weight gain and intravenous fluid requirement between the two groups remained insignificantly different.
CONCLUSION:
R-ORS was more effective in the management of acute watery diarrhea in children. Duration of diarrhea and treatment was shortened when compared to G-ORS.
AuthorsSukkrawan Intarakhao, Paskorn Sritipsukho, Kwanta Aue-u-lan
JournalJournal of the Medical Association of Thailand = Chotmaihet thangphaet (J Med Assoc Thai) Vol. 93 Suppl 7 Pg. S21-5 (Dec 2010) ISSN: 0125-2208 [Print] Thailand
PMID21298835 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
Chemical References
  • Rehydration Solutions
  • Solutions
  • Glucose
Topics
  • Administration, Oral
  • Child
  • Child, Preschool
  • Defecation
  • Dehydration (therapy)
  • Diarrhea, Infantile (therapy)
  • Female
  • Fluid Therapy
  • Glucose (administration & dosage)
  • Humans
  • Infant
  • Male
  • Oryza
  • Rehydration Solutions (therapeutic use)
  • Solutions
  • Treatment Outcome
  • Weight Gain

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