Osteoblastoma in the nasal cavity: F-18 FDG PET/CT and Tc-99m MDP 3-phase bone scan findings with pathologic correlation.

Abstract

A benign osteoblastoma of the nasal cavity is very rare. A 57-year-old woman, who had a radical hysterectomy for carcinoma of the uterine cervix 5 years ago, underwent F-18 FDG PET/CT. An expansile bone tumor with high glucose metabolism in the middle turbinate of the left nasal cavity was incidentally demonstrated. A subsequent Tc-99m methylene diphosphonate 3-phase bone scan revealed focal increased uptake of radionuclide in all 3 phases at the corresponding tumor. Histology confirmed a benign osteoblastoma that was composed of proliferating osteoblasts with woven bone spicules and rich vascular stroma. Scintigraphic findings, including F-18 FDG PET/CT and 3-phase bone scan, reflected the pathologic features well.

• Authors: Young Jin Jeong, Myung-Hee Sohn, Seok Tae Lim, Dong Wook Kim, Hwan-Jeong Jeong, Kyu Yun Jang, Chang-Yeol Yim
• Journal: Clinical nuclear medicine (Clin Nucl Med) Vol. 36 Issue 3 Pg. 214-7 (Mar 2011) ISSN: 1536-0229 [Electronic] United States
• PMID: 21285681 (Publication Type: Case Reports, Journal Article)

Chemical References

• Fluorodeoxyglucose F18
• Technetium Tc 99m Medronate

Topics

• Female
• Fluorodeoxyglucose F18
• Humans
• Middle Aged
• Nasal Cavity (diagnostic imaging, pathology)
• Nose Neoplasms (diagnostic imaging, pathology)
• Osteoblastoma (diagnostic imaging, pathology)
• Positron-Emission Tomography
• Technetium Tc 99m Medronate
• Tomography, X-Ray Computed