Two cases of drug-induced orbital inflammatory disease.

Abstract

Orbital inflammatory disease (OID) includes all inflammatory processes affecting the orbit. Although several aetiologies are recognised, a cause may not be elucidated. We describe 2 cases in which drugs (hyaluronidase and zoledronic acid) were the cause of OID. In patients with a clinical picture of OID simulating an orbital cellulitis, the recent drug history should be considered as a possible aetiology, and treatment with steroids with or without a biopsy should be considered after an infection has been excluded.

• Authors: Santiago Ortiz-Perez, Estrella Fernandez, Juan Jose Molina, Bernardo Sanchez-Dalmau, Manuel Navarro, Xavier Corretger, Jane M Olver
• Journal: Orbit (Amsterdam, Netherlands) (Orbit) Vol. 30 Issue 1 Pg. 37-9 (Jan 2011) ISSN: 1744-5108 [Electronic] England
• PMID: 21281079 (Publication Type: Case Reports, Journal Article)

Chemical References

• Bone Density Conservation Agents
• Diphosphonates
• Imidazoles
• Zoledronic Acid
• Hyaluronoglucosaminidase

Topics

• Aged
• Bone Density Conservation Agents (adverse effects)
• Cataract Extraction
• Cellulitis (diagnosis)
• Diagnosis, Differential
• Diphosphonates (adverse effects)
• Female
• Humans
• Hyaluronoglucosaminidase (adverse effects)
• Imidazoles (adverse effects)
• Inflammation (chemically induced, diagnosis)
• Orbital Diseases (chemically induced, diagnosis)
• Paget Disease, Extramammary (drug therapy)
• Zoledronic Acid