Abstract | BACKGROUND: METHODS: The study participants were 16 patients with PD who underwent bilateral STN-DBS, and 16 age-matched control patients with PD. The participants performed the IGT pre-operatively and 2-4 weeks post-operatively with on- and off-stimulation. Participants' one hundred card selections were divided into five blocks of 20 cards each. RESULTS: The total IGT score was not significantly different before surgery, on-stimulation or off-stimulation, but DBS patients tended to perform worse in the on-DBS session compared to off-DBS session (P = 0.019) only in the last block of the task. The IGT score did not correlate with levodopa equivalent dose or performance on the measures of executive function, but did correlate with self-reported depression symptoms, and active contact of stimulation. CONCLUSION: Bilateral STN-DBS may affect decision-making in acute post-operative stage.
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Authors | Genko Oyama, Yasushi Shimo, Shihoko Natori, Madoka Nakajima, Hisato Ishii, Hajime Arai, Nobutaka Hattori |
Journal | Parkinsonism & related disorders
(Parkinsonism Relat Disord)
Vol. 17
Issue 3
Pg. 189-93
(Mar 2011)
ISSN: 1873-5126 [Electronic] England |
PMID | 21276745
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2010. Published by Elsevier Ltd. |
Topics |
- Aged
- Analysis of Variance
- Case-Control Studies
- Decision Making
(physiology)
- Deep Brain Stimulation
(methods)
- Female
- Games, Experimental
- Humans
- Male
- Mental Status Schedule
- Middle Aged
- Parkinson Disease
(physiopathology, therapy)
- Severity of Illness Index
- Statistics as Topic
- Subthalamic Nucleus
(physiology)
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