Abstract |
Oncogenic osteomalacia (OO) is a rare paraneoplastic syndrome, with only 100 reported cases in the literature. The majority of OO-associated mesenchymal tumors are due to a lesion called phosphaturic mesenchymal tumor, mixed connective tissue (PMTMCT) variant. There have been only 6 reported cases of OO of the spine. With this paper the authors present a case of OO of the cervical spine in a patient who initially presented with multiple pathological fractures of unknown cause, and who eventually underwent staged C-5 spondylectomy followed by circumferential stabilization. Resection of the cervical lesion led to resolution of his hypophosphatemia and prevention of any further pathological fractures. The authors describe a rare cervical neoplasm, its treatment, and review the literature on this rare bony pathological entity.
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Authors | Murtaza Akhter, Patrick A Sugrue, Rick Bains, Yevgeniy A Khavkin |
Journal | Journal of neurosurgery. Spine
(J Neurosurg Spine)
Vol. 14
Issue 4
Pg. 453-6
(Apr 2011)
ISSN: 1547-5646 [Electronic] United States |
PMID | 21275557
(Publication Type: Case Reports, Journal Article)
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Topics |
- Cervical Vertebrae
(diagnostic imaging, surgery)
- Humans
- Male
- Middle Aged
- Neoplasms, Connective Tissue
(diagnostic imaging, surgery)
- Osteomalacia
- Paraneoplastic Syndromes
(diagnostic imaging, surgery)
- Radiography
- Spinal Neoplasms
(diagnostic imaging, surgery)
- Treatment Outcome
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