Abstract | PURPOSE: Analyze the influence of low-intensity laser therapy in the sciatic nerve regeneration of rats submitted to controlled crush through histological analysis. METHODS: Were used 20 Wistar rats, to analyze the influence of low-intensity laser therapy in the sciatic nerve regeneration, where the injury of the type axonotmesis was induced by a haemostatic clamp Crile (2nd level of the rack). The animals were randomly distributed in 2 groups. Control group (CG n = 10) and Laser group (LG n = 10). These were subdivided in 2 subgroups each, according to the euthanasia period: (CG14 - n = 5 and CG21 - n = 5) and (LG14 - n = 5 and LG21 - n = 5). At the end of treatment, the samples were removed and prepared for histological analysis, where were analyzed and quantified the following findings: Schwann cells, myelinic axons with large diameter and neurons. RESULTS: In the groups submitted to low-intensity laser therapy, were observed an increase in the number of all analyzed aspects with significance level. CONCLUSION: The irradiation with low intensity laser (904nm) influenced positively the regeneration of the sciatic nerve in Wistar rats after being injured by crush ( axonotmesis), becoming the nerve recovery more rapid and efficient.
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Authors | Cibele Nazaré da Silva Câmara, Marcus Vinicius Henriques Brito, Edvaldo Lima Silveira, Diego Sá Guimarães da Silva, Vivian Roberta Ferreira Simões, Roberto Waldesmand Farias Pontes |
Journal | Acta cirurgica brasileira
(Acta Cir Bras)
Vol. 26
Issue 1
Pg. 12-8
(Feb 2011)
ISSN: 1678-2674 [Electronic] Brazil |
PMID | 21271198
(Publication Type: Journal Article)
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Topics |
- Animals
- Low-Level Light Therapy
(methods)
- Male
- Nerve Crush
- Nerve Regeneration
(physiology, radiation effects)
- Peripheral Nerve Injuries
- Peripheral Nerves
(physiology, radiation effects)
- Random Allocation
- Rats
- Rats, Wistar
- Sciatic Nerve
(cytology, injuries, physiology)
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