Abstract | BACKGROUND: METHODS: A cross sectional study was conducted at four randomly selected hospitals in the Klang Valley from December 2008 to May 2009. Self administered questionnaire was used to obtain information on health care workers and possible risk factors. The response rate for this study was 90.8% with 954 respondents completed the questionnaire and were tested with Quantiferon TB Gold in tube for latent tuberculosis infection. Agreement between Quantiferon TB Gold in tube and Tuberculin Skin Test was assessed among 95 health care workers who consented to undergo both tests. RESULTS: The overall prevalence of latent tuberculosis infection among health care workers was 10.6% (CI: 8.6%; 12.6%). Factors significantly associated with latent tuberculosis infection were aged 35 years and older [9.49 (CI: 2.22; 40.50)], history of living in the same house with close family members or friends who had active tuberculosis [8.69 (CI: 3.00; 25.18)], worked as a nurse [4.65 (CI: 1.10; 19.65)] and being male [3.70 (CI: 1.36; 10.02)]. Agreement between Quantiferon TB Gold in tube test and tuberculin skin test at cut-off points of 10 mm and 15 mm was 50.5% and 82.1% respectively. However, Kappa-agreement was poor for both cut-off points. CONCLUSION:
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Authors | Shaharudin Rafiza, Krishna Gopal Rampal, Aris Tahir |
Journal | BMC infectious diseases
(BMC Infect Dis)
Vol. 11
Pg. 19
(Jan 18 2011)
ISSN: 1471-2334 [Electronic] England |
PMID | 21244645
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Adolescent
- Adult
- Cross-Sectional Studies
- Female
- Health Personnel
(statistics & numerical data)
- Humans
- Infectious Disease Transmission, Patient-to-Professional
(statistics & numerical data)
- Latent Tuberculosis
(diagnosis, epidemiology, transmission)
- Malaysia
(epidemiology)
- Male
- Middle Aged
- Occupational Exposure
(statistics & numerical data)
- Prevalence
- Risk Factors
- Tuberculin Test
- Young Adult
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