Abstract | BACKGROUND: Although bariatric surgery is known to exert favorable effects on dyslipidemia, few studies have systematically considered how the demographic variables might modulate the outcomes. The aim of the present study was to examine the interactive effects of gender, age, and surgery type on dyslipidimia in bariatric surgery patients at a tertiary hospital in the United States. METHODS: In a retrospective review of 294 patients who had undergone laparoscopic Roux-en-Y gastric bypass (LRYGB) or laparoscopic adjustable gastric bypass (LAGB), we examined the changes in lipid profiles and antihyperlipidemic use for ≤4 years postoperatively. The data were analyzed using longitudinal mixed modeling methods, in which the effects on lipid concentrations and medication use were tested in models with gender, surgery type, age, postoperative duration, and all possible interactions entered as factors. RESULTS: CONCLUSION: Our results have demonstrated that bariatric surgery imparts a pronounced improvement in the blood lipid profile of recipients; however, these effects might be moderated by other factors, such as age and gender, independently of the baseline weight status of the patients.
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Authors | Rachael J Pohle-Krauza, Michele L McCarroll, Debbie D Pasini, Adrian G Dan, John G Zografakis |
Journal | Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
(Surg Obes Relat Dis)
2011 Mar-Apr
Vol. 7
Issue 2
Pg. 170-5
ISSN: 1878-7533 [Electronic] United States |
PMID | 21237722
(Publication Type: Comparative Study, Journal Article)
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Copyright | Copyright © 2011 American Society for Metabolic and Bariatric Surgery. Published by Elsevier Inc. All rights reserved. |
Chemical References |
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Topics |
- Adult
- Age Factors
- Aged
- Anastomosis, Roux-en-Y
(adverse effects, methods)
- Dyslipidemias
(blood, epidemiology, etiology)
- Female
- Follow-Up Studies
- Gastric Bypass
(adverse effects, methods)
- Humans
- Incidence
- Laparoscopy
- Lipids
(blood)
- Male
- Middle Aged
- Obesity, Morbid
(blood, complications, surgery)
- Ohio
(epidemiology)
- Prognosis
- Retrospective Studies
- Risk Factors
- Sex Factors
- Young Adult
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