Abstract | CONTEXT: CASE PRESENTATION: DISCUSSION: The most striking aspect of this case is that despite use of chelators, a dramatic increase in blood mercury level occurred. We discuss the rationale for combined use of chelators with hemodialysis and other treatments such as plasma exchange in the setting of acute mercury poisoning. This case also illustrated the potentially serious side effects of the chelation drug DMSA, and we discuss the potential relevance of dosing frequency to the occurrence rates of such side effects. RELEVANCE TO CLINICAL PRACTICE: Despite the tragic outcome, on review of case literature, we believe this case provides valuable lessons concerning the use of DMSA and DMPS to treat mercury toxicity, particularly with regard to the combined use of chelation agents and hemodialysis.
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Authors | Tarek Alhamad, James Rooney, Azikiwe Nwosu, Jay Maccombs, Young-Sik Kim, Vani Shukla |
Journal | International urology and nephrology
(Int Urol Nephrol)
Vol. 44
Issue 2
Pg. 647-51
(Apr 2012)
ISSN: 1573-2584 [Electronic] Netherlands |
PMID | 21234679
(Publication Type: Case Reports, Journal Article)
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Topics |
- Adult
- Chronic Disease
- Diagnosis, Differential
- Fatal Outcome
- Humans
- Male
- Mercury Poisoning
(complications, diagnosis)
- Renal Insufficiency
(diagnosis, etiology)
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