| Abstract |
Here we present antiestrogenic effects of Knotolan, a new dietary lignan from Abies sibirica raw material. Knotolan abolished growth-stimulating effects of 17β-estradiol on hormone-dependent MCF-7 cells. |
| Authors | O S Zhukova, L V Fetisova, A V Trishin, N Yu Anisimova, A M Scherbakov, A E Shcherbakov, D V Yashunskii, D E Tsvetkov, V M Men'shov, M V Kiselevskii, N E Nifant'ev |
| Journal | Bulletin of experimental biology and medicine
(Bull Exp Biol Med)
Vol. 149
Issue 4
Pg. 511-4
(Oct 2010)
ISSN: 1573-8221 [Electronic] United States |
| PMID | 21234454
(Publication Type: Journal Article)
|
| Chemical References |
- Butylene Glycols
- Lignans
- Estradiol
- secoisolariciresinol
|
| Topics |
- Abies
(chemistry)
- Breast Neoplasms
(drug therapy)
- Butylene Glycols
(therapeutic use)
- Cell Line, Tumor
- Cell Proliferation
(drug effects)
- Estradiol
(pharmacology)
- Female
- Humans
- Lignans
(therapeutic use)
- Neoplasms, Hormone-Dependent
(drug therapy)
|
