The present study investigated the use of a novel
hyaluronic acid serum in combination with a cream comprising a mixture of human
growth factors in conjunction with the micro
laser peel procedure for skin
rejuvenation. After preconditioning the face with the
hyaluronic acid serum followed by the cream twice daily for one month, 15 female volunteers between 35 to 65 years of age with demonstrable facial wrinkling received a micro
laser peel on the entire face using an
erbium-doped
yttrium aluminium garnet
laser. Immediately following the
laser procedure, the subjects applied the test products twice daily until the second
laser peel one month later. Immediately following the second procedure, the subjects reapplied the test products for another month. In the large majority of subjects,
erythema or
edema, crusts or erosions, and transitory stinging or burning sensations after the micro
laser peel were minimal or mild when the skin was treated with the serum followed by the cream. The micro
laser peel in conjunction with the test products helped to significantly improve
hyperpigmentation, wrinkles, and texture as compared to before treatment. This study with the micro
laser peel device demonstrated that a novel
hyaluronic acid serum combined with the human
growth factor cream can be successfully used for skin
rejuvenation in conjunction with light-to-medium invasive
laser skin treatments.