Persistence of Leishmania donovani antibodies in past visceral leishmaniasis cases in India.

Abstract

The persistence of anti-Leishmania donovani antibodies in past visceral leishmaniasis (VL) cases was retrospectively assessed by means of the direct agglutination test (DAT) and the rK39 enzyme-linked immunosorbent assay (ELISA). Antibody titers remained high for an extended period of time in past cases of VL. These results highlight the need to carefully elicit the history of patients with VL symptoms.

• Authors: Kamlesh Gidwani, Albert Picado, Bart Ostyn, Shri Prakash Singh, Rajiv Kumar, Basudha Khanal, Veerle Lejon, François Chappuis, Marleen Boelaert, Shyam Sundar
• Journal: Clinical and vaccine immunology : CVI (Clin Vaccine Immunol) Vol. 18 Issue 2 Pg. 346-8 (Feb 2011) ISSN: 1556-679X [Electronic] United States
• PMID: 21159922 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Antibodies, Protozoan

Topics

• Adolescent
• Adult
• Aged
• Aged, 80 and over
• Agglutination Tests
• Antibodies, Protozoan (blood)
• Child
• Child, Preschool
• Enzyme-Linked Immunosorbent Assay
• Female
• Humans
• India
• Infant
• Leishmania donovani (immunology)
• Leishmaniasis, Visceral (immunology)
• Male
• Middle Aged
• Retrospective Studies
• Young Adult