Cushing's syndrome in pregnancy with a severe maternal complication: a case report.

Abstract

Cushing's syndrome (CS) in pregnancy may be confused with a complication of pregnancy, such as pre-eclampsia or gestational diabetes. We managed a case of CS in pregnancy that was considered to be severe pre-eclampsia due to uncontrolled hypertension. The fetus was delivered via emergency cesarean section at 31 weeks' gestation because of severe pre-eclampsia and pulmonary edema. The parturient was admitted to the intensive care unit for severe maternal complications, including pulmonary hemorrhage, acute renal failure, disseminated intravascular coagulopathy, and congestive heart failure. A spine magnetic resonance image and 99m-technetium whole-body scan obtained postpartum showed multiple thoracolumbar spine compression fractures (Deleted; t-2,5,8,10,11, and -12; and L-1,2,3,4, and -5), multiple rib fractures, and a left iliac bone fracture due to osteoporosis. As a result of diagnosing CS after delivery, an adrenal cortical adenoma of the right adrenal gland was demonstrated and a laparoscopic adrenalectomy was successfully performed.

• Authors: Won Jun Choi, Tae Sik Jung, Won Young Paik
• Journal: The journal of obstetrics and gynaecology research (J Obstet Gynaecol Res) Vol. 37 Issue 2 Pg. 163-7 (Feb 2011) ISSN: 1447-0756 [Electronic] Australia
• PMID: 21159041 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2010 The Authors. Journal of Obstetrics and Gynaecology Research © 2010 Japan Society of Obstetrics and Gynecology.

Topics

• Adrenal Cortex Neoplasms (complications, diagnosis, surgery)
• Adrenocortical Adenoma (complications, diagnosis, surgery)
• Adult
• Cushing Syndrome (diagnosis, etiology, physiopathology, surgery)
• Diagnosis, Differential
• Female
• Hemorrhage
• Humans
• Hypertension
• Lung Diseases
• Osteoporosis
• Pregnancy
• Pregnancy Complications (diagnosis, etiology, physiopathology, surgery)
• Treatment Outcome