Incidence of common pyocin types of Pseudomonas aeruginosa from patients with cystic fibrosis and chronic airways diseases.

Abstract

We sought evidence to determine if particular strains of Pseudomonas aeruginosa have a predilection for pulmonary colonisation in patients with cystic fibrosis (CF). The incidence of common pyocin types in non-CF isolates (74%) was similar to that noted in previous reports but differed significantly (X2 = 16.7, p less than 0.001) from the incidence of 40% observed in CF isolates. A retrospective analysis of respiratory isolates also indicated a relatively low incidence of common pyocin types (44%) in isolates from non-CF patients with chronic airways diseases and this incidence also differed significantly from that observed (73%) in other respiratory isolates from patients in the same hospital. These observations suggest that a subpopulation of P. aeruginosa exists which has a predilection for pulmonary colonisation in CF and other chronic pulmonary diseases and may assist in identification of factors affecting bacterial colonisation.

• Authors: M W Tredgett, C Doherty, J R Govan
• Journal: Journal of medical microbiology (J Med Microbiol) Vol. 32 Issue 3 Pg. 169-72 (Jul 1990) ISSN: 0022-2615 [Print] England
• PMID: 2115590 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Bacteriocins
• Pyocins

Topics

• Bacteriocins (classification)
• Cystic Fibrosis (complications, microbiology)
• Humans
• Incidence
• Lung Diseases, Obstructive (complications, microbiology)
• Pseudomonas Infections (complications)
• Pseudomonas aeruginosa (classification)
• Pyocins (classification)
• Sputum (microbiology)