Hailey-Hailey disease treatment with Botulinum toxin type A.

Abstract

Two sisters with recurrent lesions, one on axillae and other on the groin, and with limited response to classical treatments were treated with injections botulinum toxin type A. We observed marked improvement in the patient treated in the groin and complete remission in the patient treated in the axillae. It was possible to spare the use of systemic antibiotics and topical corticosteroids. The high cost is a restrictive factor to routine use and large studies are necessary to access efficacy and cost benefit profile.

• Authors: Giancarlo Rezende Bessa, Thaís Corsetti Grazziotin, Ana Paula Manzoni, Magda Blessmann Weber, Renan Rangel Bonamigo
• Journal: Anais brasileiros de dermatologia (An Bras Dermatol) 2010 Sep-Oct Vol. 85 Issue 5 Pg. 717-22 ISSN: 1806-4841 [Electronic] Spain
• PMID: 21152802 (Publication Type: Case Reports, Journal Article)

Chemical References

• Dermatologic Agents
• Botulinum Toxins, Type A

Topics

• Aged
• Botulinum Toxins, Type A (therapeutic use)
• Chemotherapy, Adjuvant
• Dermatologic Agents (therapeutic use)
• Female
• Humans
• Middle Aged
• Pemphigus, Benign Familial (drug therapy)
• Treatment Outcome