Monitoring sleep-wake rhythm with actigraphy in patients on continuous positive airway pressure therapy.

Abstract

BACKGROUND:

Continuous positive airway pressure (CPAP) therapy has been shown to be effective in alleviating the underlying obstruction as well as reducing patients' excessive sleepiness and improving their functioning and health-related quality of life. However, residual excessive sleepiness is observed in some patients even though CPAP therapy eliminates sleep apnea and desaturation.

OBJECTIVES:

The aim of this study was to determine the prognostic effect of actigraphic sleep-wake rhythm evaluation in the management of patients with obstructive sleep apnea syndrome (OSAS) treated with CPAP.

METHODS:

Eighteen patients with OSAS diagnosed by standard polysomnography (PSG; 48.1 ± 12.5 years) were enrolled in this study. The sleep-wake parameters were determined by actigraphy before and after 1 month of CPAP treatment, and results were compared with PSG data. In addition, data obtained before CPAP were compared with those measured after 1 month of CPAP treatment.

RESULTS:

The total sleep time (TST) and sleep efficiency using PSG were significantly correlated with those using actigraphy. Bland-Altman plots of TST and sleep efficiency confirmed good agreement between PSG and actigraphy data. Sleep efficiency significantly improved following CPAP compared to baseline, and sleep fragmentation and sleep fragmentation >5 min determined by actigraphy were significantly lower during CPAP therapy than at baseline. Movement was significantly lower on CPAP therapy than at baseline.

CONCLUSIONS:

Actigraphy provides a valuable sleep-wake rhythm assessment in outpatients with OSAS where PSG is difficult to perform.

• Authors: Masafumi Otake, Seiko Miyata, Akiko Noda, Yasuo Koike, Yuki Hara, Mari Sugiura, Makoto Minoshima, Jun Kojima, Seiichi Nakata, Tsutomu Nakashima
• Journal: Respiration; international review of thoracic diseases (Respiration) Vol. 82 Issue 2 Pg. 136-41 ( 2011) ISSN: 1423-0356 [Electronic] Switzerland
• PMID: 21135533 (Publication Type: Journal Article)
• Copyright: Copyright © 2010 S. Karger AG, Basel.

Topics

• Actigraphy
• Continuous Positive Airway Pressure
• Humans
• Polysomnography
• Sleep (physiology)
• Sleep Deprivation (diagnosis)