Transmission of varicella vaccine virus to a non-family member in China.

Abstract	A 23-year-old teacher presented to hospital with a mild case of varicella. VZV vaccine strain vOka that resembles Varilrix but not Varivax or Biken strains was isolated from the skin lesion of the patient and was identified by single nucleotide polymorphism (SNP) analysis. The teacher denied having varicella vaccine before. Retrospective analysis suggests the transmission came from a pupil who developed zoster 13 months after varicella vaccine Varilrix. This is the first report in China in which an adult with varicella was attributable to vaccine virus and the 6th report of transmission of vaccine virus to a susceptible adult around the world.
Authors	Lin Gan, Mingli Wang, Sen Yang, Anne A Gershon, Jason J Chen
Journal	Vaccine (Vaccine) Vol. 29 Issue 11 Pg. 2015-7 (Mar 03 2011) ISSN: 1873-2518 [Electronic] Netherlands
PMID	21134454 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
Copyright	Copyright © 2010 Elsevier Ltd. All rights reserved.
Chemical References	Chickenpox Vaccine
Topics	Chickenpox (transmission) Chickenpox Vaccine (adverse effects) China Female Herpesvirus 3, Human (genetics) Humans Polymorphism, Single Nucleotide Young Adult

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