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No severe pulmonary vein stenosis after extensive encircling pulmonary vein isolation: 12-month follow-up with 3D computed tomography.

Abstract
Few studies have explored the utility of local electrogram-guided extensive encircling pulmonary vein isolation (EEPVI) by analyzing the pulmonary vein (PV) anatomy and occurrence of stenosis using multidetector computed tomography (MDCT). One hundred seventy-six paroxysmal atrial fibrillation (AF) patients underwent EEPVI with a double lasso technique. MDCT was performed in all patients before and at 3, 6 and 12 months after the ablation procedures to screen for PV stenosis. PV stenosis was defined as a >30% reduction in its diameter. A total of 700 PVs were analyzed. PV stenosis was observed in 15 of 700 PVs (2.1%). All stenoses were mild (mean 34.5 ± 3.3%). They were all asymptomatic, and none required treatment. After 12 months of follow-up, the PV narrowing regressed significantly compared with that at 3 months in the patients with PV stenosis (34.5 ± 3 to 30.4 ± 5%, P < 0.05). The remaining PVs exhibited a stable anatomy, and there was no significant progression of the PV narrowing. The results of this study demonstrated that detectable PV stenosis occurred in 2.1% of the PVs, and all stenoses were mild. Moreover, a significant regression of the PV narrowing was observed after 12-months of follow-up. This indicates that the local electrocardiogram-guided EEPVI was relatively safe regarding severe PV stenosis.
AuthorsShingo Maeda, Yoshito Iesaka, Kiyoshi Otomo, Kikuya Uno, Yasutoshi Nagata, Kenji Suzuki, Hitoshi Hachiya, Masahiko Goya, Atsushi Takahashi, Hideomi Fujiwara, Mitsuaki Isobe
JournalHeart and vessels (Heart Vessels) Vol. 26 Issue 4 Pg. 440-8 (Jul 2011) ISSN: 1615-2573 [Electronic] Japan
PMID21132307 (Publication Type: Journal Article)
Topics
  • Adult
  • Aged
  • Atrial Fibrillation (diagnostic imaging, surgery)
  • Catheter Ablation (adverse effects, methods)
  • Chi-Square Distribution
  • Electrophysiologic Techniques, Cardiac
  • Female
  • Humans
  • Japan
  • Male
  • Middle Aged
  • Phlebography (methods)
  • Predictive Value of Tests
  • Pulmonary Veins (diagnostic imaging, surgery)
  • Pulmonary Veno-Occlusive Disease (diagnostic imaging, etiology)
  • Risk Assessment
  • Risk Factors
  • Severity of Illness Index
  • Time Factors
  • Tomography, X-Ray Computed
  • Treatment Outcome

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