Abstract | BACKGROUND: CASE REPORT: We report a case of an 85-year-old white man with decreased visual acuities of 20/70 in the right eye (O.D.) and 20/150 in the left eye (O.S.) secondary to dry AMD O.D. and wet AMD with a fibrovascular PED O.S. The patient underwent treatment with an intravitreal bevacizumab injection O.S. Six weeks after the initial injection, the patient returned with further declining vision in the left eye secondary to an RPE tear. CONCLUSION: Intravitreal bevacizumab has proven to be an effective treatment for choroidal neovascularization and shows a significant improvement of vision for wet AMD patients. However, there are risks associated with the procedure. One of the most visually significant is an RPE tear, which can occur at an incidence rate as high as 17%. Optometrists should be aware of this rare, but serious, complication associated with anti- VEGF treatment for wet AMD.
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Authors | Brenda Yeh, Steven Ferrucci |
Journal | Optometry (St. Louis, Mo.)
(Optometry)
Vol. 82
Issue 3
Pg. 152-7
(Mar 2011)
ISSN: 1558-1527 [Electronic] United States |
PMID | 21130699
(Publication Type: Case Reports, Journal Article, Research Support, U.S. Gov't, Non-P.H.S.)
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Copyright | Published by Elsevier Inc. |
Chemical References |
- Angiogenesis Inhibitors
- Antibodies, Monoclonal
- Antibodies, Monoclonal, Humanized
- Bevacizumab
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Topics |
- Aged, 80 and over
- Angiogenesis Inhibitors
(administration & dosage, adverse effects)
- Antibodies, Monoclonal
(administration & dosage, adverse effects)
- Antibodies, Monoclonal, Humanized
- Bevacizumab
- Choroidal Neovascularization
(drug therapy, etiology)
- Humans
- Intravitreal Injections
- Macular Degeneration
(complications)
- Male
- Retinal Perforations
(chemically induced)
- Retinal Pigment Epithelium
(drug effects)
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