Abstract | OBJECTIVE: METHODS: We studied 15 consecutive patients, who presented with their first acute anterior STEMI within 6 hours after onset of symptoms, and in whom LV pressure-volume (PV) loops were directly obtained during pPCI. Immediate effects of pPCI on LV function were compared between patients with (n = 5) and without (n = 10) occurrence of AIVR after reperfusion, as well as the direct effects of AIVR on LV function compared to sinus rhythm. RESULTS: Patients with reperfusion-induced AIVR showed more pronounced diastolic LV dysfunction before the onset of the arrhythmia, i.e., a delayed active relaxation expressed by Tau (53 ± 15 vs. 39 ± 6 ms; p = 0.03), a worse compliance curve (p = 0.01), and a higher end-diastolic stiffness (p = 0.07). At the end of the procedure, AIVR patients showed less improvement in diastolic LV function, indicated by a downward shift of the compliance curve (-3.1 ± 2.3 vs. -7.5 ± 1.4 mmHg; p = 0.001), a decrease in end-diastolic stiffness (13 ± 18 vs. 34 ± 15%; p = 0.03) and end-diastolic pressure (12 ± 8 vs. 29 ± 19%; p = 0.07). CONCLUSION:
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Authors | Maurice Remmelink, Ronak Delewi, Ze Yie Yong, Jan J Piek, Jan Baan Jr |
Journal | The Journal of invasive cardiology
(J Invasive Cardiol)
Vol. 22
Issue 12
Pg. 574-8
(Dec 2010)
ISSN: 1557-2501 [Electronic] United States |
PMID | 21127361
(Publication Type: Comparative Study, Journal Article)
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Topics |
- Accelerated Idioventricular Rhythm
(etiology, physiopathology)
- Aged
- Angioplasty, Balloon, Coronary
(methods)
- Diastole
(physiology)
- Electrocardiography
- Female
- Heart Ventricles
(physiopathology)
- Humans
- Male
- Middle Aged
- Myocardial Infarction
(therapy)
- Myocardial Reperfusion
(adverse effects)
- Retrospective Studies
- Ventricular Dysfunction, Left
(diagnosis, physiopathology)
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