Demonstration of Marek's disease tumor-associated surface antigen in chickens infected with nononcogenic Marek's disease virus and herpesvirus of turkeys.

The presence of Marek's disease tumor-associated surface antigen (MATSA) was demonstrated on spleen cells from P-line chickens inoculated 5--6 days earlier with herpesvirus of turkeys and SB-1 (a nononcogenic Marek's disease virus). Antisera against MATSA expressed on five Marek's disease lymphoblastoid cell lines were able to recognize the MATSA present on SB-1-infected spleen cells. No viral membrane antigens and only a low incidence of viral internal antigens could be demonstrated.
AuthorsK A Schat, B W Calnek
JournalJournal of the National Cancer Institute (J Natl Cancer Inst) Vol. 61 Issue 3 Pg. 855-7 (Sep 1978) ISSN: 0027-8874 [Print] UNITED STATES
PMID211242 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Antigens, Neoplasm
  • Antigens, Surface
  • Antigens, Viral
  • Animals
  • Antigens, Neoplasm
  • Antigens, Surface
  • Antigens, Viral
  • Chickens
  • Herpesviridae Infections (immunology)
  • Immunity
  • Marek Disease (immunology)
  • Spleen (immunology)

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