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Metastasis suppression: a role of the Dice(r).

Abstract
Recent studies have implicated the microRNA biogenesis enzyme Dicer as a suppressor of breast carcinoma metastasis and elucidated upstream signaling pathways that control Dicer levels.
AuthorsScott Valastyan, Robert A Weinberg
JournalGenome biology (Genome Biol) Vol. 11 Issue 11 Pg. 141 ( 2010) ISSN: 1474-760X [Electronic] England
PMID21118581 (Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)
Copyright© 2010 BioMed Central Ltd
Chemical References
  • MicroRNAs
  • TP63 protein, human
  • Trans-Activators
  • Transcription Factors
  • Tumor Suppressor Proteins
  • Ribonuclease III
Topics
  • Breast Neoplasms (genetics, metabolism)
  • Genes, Suppressor
  • Humans
  • MicroRNAs (genetics, metabolism)
  • Neoplasm Metastasis (genetics)
  • Ribonuclease III (genetics, metabolism)
  • Signal Transduction
  • Trans-Activators (genetics, metabolism)
  • Transcription Factors
  • Tumor Suppressor Proteins (genetics, metabolism)
  • Up-Regulation

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