Oral manifestations of hematologic and nutritional diseases.

Abstract

Oral manifestations of hematologic and nutritional deficiencies can affect the mucous membranes, teeth, periodontal tissues, salivary glands, and perioral skin. This article reviews common oral manifestations of hematologic conditions starting with disorders of the white blood cells including cyclic hematopoiesis (cyclic neutropenia), leukemias, lymphomas, plasma cell dyscrasias, and mast cell disorders; this is followed by a discussion of the impact of red blood cell disorders including anemias and less common red blood cell dyscrasias (sickle cell disease, hemochromatosis, and congenital erythropoietic porphyria) as well as thrombocytopenia. Several nutritional deficiencies exhibit oral manifestations. The authors specifically discuss the impact of water-soluble vitamins (B2, B3, B6, B9, B12, and C), fat-soluble vitamins (A, D, and K) and the eating disorders anorexia nervosa and bulimia nervosa on the oral mucosa.

• Authors: Bethanee J Schlosser, Megan Pirigyi, Ginat W Mirowski
• Journal: Otolaryngologic clinics of North America (Otolaryngol Clin North Am) Vol. 44 Issue 1 Pg. 183-203, vii (Feb 2011) ISSN: 1557-8259 [Electronic] United States
• PMID: 21093629 (Publication Type: Journal Article, Review)
• Copyright: Copyright © 2011 Elsevier Inc. All rights reserved.

Topics

• Avitaminosis (complications)
• Feeding and Eating Disorders (complications)
• Hematologic Diseases (complications)
• Humans
• Mouth Diseases (diagnosis, etiology)