Pharmacologic testing in Horner's syndrome - a new paradigm.

Abstract

For more than three decades, topical cocaine has been used to confirm the diagnosis and hydroxyamphetamine to localise the causative lesion in oculosympathetic palsy or Horner's syndrome. More recently, other drugs have demonstrated the ability to point to the diagnosis or anatomical site. Apraclonidine and phenylephrine, given their similar diagnostic efficacy and increased availability, may have superseded cocaine and hydroxyamphetamine as first-line pharmacological testing agents in Horner's syndrome.

• Authors: Derrick P Smit
• Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde (S Afr Med J) Vol. 100 Issue 11 Pg. 738-40 (Nov 09 2010) ISSN: 0256-9574 [Print] South Africa
• PMID: 21081027 (Publication Type: Journal Article)

Chemical References

• Cocaine

Topics

• Cocaine
• Horner Syndrome
• Humans