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An inflammatory reaction surrounding molluscum contagiosum as possible manifestation of immune reconstitution inflammatory syndrome in HIV infection.

Abstract
Highly active antiretroviral therapy can restore specific immune responses and control of microorganism infections in human immunodeficiency virus-positive patients. This immune recovery may cause an inflammatory reaction to microbial and autoimmune antigens known as immune reconstitution inflammatory syndrome. We describe a clinical case with an intense inflammatory response surrounding molluscum contagiosum after highly active antiretroviral therapy. The clinical and laboratory findings suggested that the reaction was due to immune reconstitution inflammatory syndrome occurring during a period of immune recovery in a child with acquired immune deficiency syndrome.
AuthorsVânia Oliveira de Carvalho, Cristina Rodrigues Cruz, Lúcia Noronha, Kerstin Taniguchi Abagge, Hermênio Cavalcante Lima
JournalPediatric dermatology (Pediatr Dermatol) 2010 Nov-Dec Vol. 27 Issue 6 Pg. 631-4 ISSN: 1525-1470 [Electronic] United States
PMID21078110 (Publication Type: Case Reports, Journal Article)
Copyright© 2010 Wiley Periodicals, Inc.
Topics
  • Antiretroviral Therapy, Highly Active
  • Biopsy
  • Child
  • Dermatitis (immunology, pathology, virology)
  • HIV Infections (drug therapy, immunology)
  • Humans
  • Immune Reconstitution Inflammatory Syndrome (immunology, pathology)
  • Immunocompetence
  • Male
  • Molluscum Contagiosum (immunology, pathology)

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