Abstract | BACKGROUND AND OBJECTIVES: MATERIALS & METHODS: After surgery, patients with breast cancer received LED photomodulation or sham treatments in conjunction with three-dimensional conformal RT. Reactions were evaluated using standardized photographs graded according to National Cancer Institute criteria. RESULTS: In the LED treatment group (n=18), no patients had grade 0 reactions, six (33.3%) had grade 1 reactions, 12 (66.7%) had grade 2 reactions, and none had a grade 3 reaction. In the sham treatment group (n=15), one (6.6%) patient had a grade 0 reaction, four (26.7%) had grade 1 reactions, 9 (60.0%) had grade 2 reactions, and one (6.7%) had a grade 3 reaction. Two (11.1%) patients in the LED treatment group and one (6.7%) in the control group had to interrupt treatment. Differences between groups were not statistically significant. CONCLUSION: LED photomodulation did not reduce the incidence of radiation-induced skin reactions or interruptions in therapy.
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Authors | Douglas Fife, David J Rayhan, Shahdad Behnam, Arisa Ortiz, Laila Elkeeb, Lisa Aquino, D Eduardo Roa, Nilam Ramsinghani, Jeffrey Kuo, Robert Newcomb, Christopher B Zachary, Kristen M Kelly |
Journal | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
(Dermatol Surg)
Vol. 36
Issue 12
Pg. 1921-7
(Dec 2010)
ISSN: 1524-4725 [Electronic] United States |
PMID | 21070458
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Copyright | © 2010 by the American Society for Dermatologic Surgery, Inc. |
Topics |
- Breast Neoplasms
(radiotherapy)
- Chi-Square Distribution
- Double-Blind Method
- Female
- Humans
- Phototherapy
(instrumentation, methods)
- Prospective Studies
- Radiodermatitis
(etiology, prevention & control)
- Surveys and Questionnaires
- Thermoluminescent Dosimetry
- Treatment Outcome
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