[Massive pulmonary thromboembolism treated successfully with streptokinase. Report of one case].

Massive pulmonary thromboembolism has a high mortality. Early thrombolysis is the treatment of choice. We report a 79-year-old man admitted in shock. A chest angio-CAT scan showed a massive pulmonary thromboembolism. A transthoracic echocardiography showed a right cardiac dysfunction. Although the patient was in hemodynamic instability, he was subjected to thrombolysis with streptokinase, assisted with noradrenaline support and invasive mechanical ventilation. Parenteral anticoagulation was started thereafter. A second echocardiography, performed 72 hours later showed an improvement in right ventricular function. The patient had a nosocomial pneumonia that was treated. Noradrenalin and mechanical ventilation were discontinued nine and 15 days after thrombolysis. A new angio-CAT scan, 23 days after the procedure, was normal. The patient was discharged in good conditions 27 days after admission.
AuthorsJosé Luis Leal, Pilar Lora, Giovanni Enciso, Enrique Reynolds
JournalRevista médica de Chile (Rev Med Chil) Vol. 138 Issue 7 Pg. 856-61 (Jul 2010) ISSN: 0034-9887 [Print] Chile
Vernacular TitleTromboembolismo pulmonar masivo con respuesta exitosa a trombolisis farmacológica. Caso clínico.
PMID21043082 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Fibrinolytic Agents
  • Streptokinase
  • Aged
  • Fibrinolytic Agents (therapeutic use)
  • Humans
  • Male
  • Pulmonary Embolism (diagnosis, drug therapy)
  • Streptokinase (therapeutic use)
  • Tomography, X-Ray Computed

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