[Changes in blood viscosity and erythrocyte deformability in patients with dyslipidemia treated with binifibrate].

Abstract

31 patients afflicted with primary hyperlipidemia who did not improve after 30 days on a diet were treated with 1800 mg/day of binifibrate. We measured the total cholesterol level and triglyceridemia, as well as blood viscosity and red cell deformability at day 0, 30, 60, 90 of treatment. We found a statistically significant decrease in cholesterol and triglyceride levels as well as blood viscosity, and an increment of red cell deformability which improved the circulatory dynamisms augmentin the tissular perfusion in these patients.

• Authors: M Labiós Gómez, M Romero Simo, F Gabriel Botella, H Martín Valles, M Morera Llorca, J Freixas Ventura
• Journal: Anales de medicina interna (Madrid, Spain : 1984) (An Med Interna) Vol. 7 Issue 10 Pg. 517-21 (Oct 1990) ISSN: 0212-7199 [Print] Spain
• Vernacular Title: Modificaciones de la viscosidad de la sangre y deformabilidad eritrocitaria en pacientes dislipémicos tratados con binifibrato.
• PMID: 2104097 (Publication Type: English Abstract, Journal Article)

Chemical References

• Hypolipidemic Agents
• Nicotinic Acids
• binifibrate

Topics

• Aged
• Blood Viscosity (drug effects)
• Erythrocyte Deformability (drug effects)
• Female
• Humans
• Hyperlipidemias (blood, drug therapy)
• Hypolipidemic Agents (pharmacology, therapeutic use)
• Male
• Middle Aged
• Nicotinic Acids (pharmacology, therapeutic use)