Biologically active secondary metabolites from marine cyanobacteria.

Abstract

Marine cyanobacteria are a rich source of complex bioactive secondary metabolites which derive from mixed biosynthetic pathways. Recently, several marine cyanobacterial natural products have garnered much attention due to their intriguing structures and exciting anti-proliferative or cancer cell toxic activities. Several other recently discovered secondary metabolites exhibit insightful neurotoxic activities whereas others are showing pronounced anti-inflammatory activity. A number of anti-infective compounds displaying activity against neglected diseases have also been identified, which include viridamides A and B, gallinamide A, dragonamide E, and the almiramides.

• Authors: Joshawna K Nunnery, Emily Mevers, William H Gerwick
• Journal: Current opinion in biotechnology (Curr Opin Biotechnol) Vol. 21 Issue 6 Pg. 787-93 (Dec 2010) ISSN: 1879-0429 [Electronic] England
• PMID: 21030245 (Publication Type: Journal Article, Research Support, N.I.H., Extramural, Review)
• Copyright: Copyright © 2010. Published by Elsevier Ltd.

Chemical References

• Anti-Infective Agents
• Anti-Inflammatory Agents
• Biological Products

Topics

• Anti-Infective Agents (chemistry, isolation & purification)
• Anti-Inflammatory Agents (chemistry, isolation & purification)
• Biological Products (chemistry, isolation & purification)
• Cyanobacteria (metabolism)
• Marine Biology (methods)