Usefulness of stenting in aortic coarctation in patients with the Turner syndrome.

Abstract

We report our experience with stent implantation for treatment of aortic coarctation in patients with Turner syndrome. Ten consecutive patients with Turner syndrome and aortic coarctation (median age 12 years, range 9 to 24) underwent coarctation stenting. Of these, 6 patients were treated for isolated coarctation and 4 for recurrent coarctation (3 after balloon dilation and 1 after balloon dilation and surgical repair). Bare metal stents were implanted in 7 patients and covered stents in 3. Immediately after stent implantation, peak systolic gradient decreased from 46.1 ± 24.3 to 1.9 ± 2.1 mm Hg (p <0.001). Aortic diameter at coarctation site increased from 5.1 ± 3.2 to 15.3 ± 2.0 mm after stenting (p <0.001). There were no deaths or procedure-related complications. During a median follow-up of 30.5 months, no patient developed restenosis. Two patients developed late aortic aneurysms at the coarctation site. In conclusion, stent implantation for aortic coarctation in patients with Turner syndrome appears to be a safe and effective alternative to surgical repair. Larger cohorts and longer-term follow-up are required to determine the effects of the procedure on the aortic wall.

• Authors: Keyhan Sayadpour Zanjani, Basil D Thanopoulos, Alejandro Peirone, Luis Alday, Georgios Giannakoulas
• Journal: The American journal of cardiology (Am J Cardiol) Vol. 106 Issue 9 Pg. 1327-31 (Nov 01 2010) ISSN: 1879-1913 [Electronic] United States
• PMID: 21029833 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2010 Elsevier Inc. All rights reserved.

Topics

• Adolescent
• Aortic Coarctation (therapy)
• Catheterization
• Child
• Female
• Humans
• Recurrence
• Stents
• Treatment Outcome
• Turner Syndrome (therapy)
• Young Adult