[The clinico-morphological validation of the pathogenetic treatment of industrial eye burns].

Abstract

The paper generalizes and analyses experimental results obtained in 60 eyes of 30 rabbits after induced burn by means of epichlorhydrine that is widely used in chemical industry and produces industrial burns of the eye in 20% of all burns in the town of Sumgait. Clinico-morphologic researches allowed to reveal peculiarities of pathogenesis of severe eye burns produced by epichlorhydrine causing toxic lesions of the iris and to substantiate effectiveness of hordox used in such cases, that has not only antiproteolytic, but also antiinflammatory, cytotoxic action on the burn process.

• Authors: I P Khoroshilova, L V Ilatovskaia, G G Bordiugova, F S Gakhramanov
• Journal: Oftalmologicheskii zhurnal (Oftalmol Zh) Issue 6 Pg. 358-62 ( 1990) ISSN: 0030-0675 [Print] Ukraine
• Vernacular Title: Kliniko-morfologicheskoe obosnovanie patogeneticheskogo lecheniia promyshlennykh ozhogov glaz.
• PMID: 2100780 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Trypsin Inhibitors
• Epichlorohydrin
• gordox
• Aprotinin

Topics

• Accidents, Occupational
• Animals
• Aprotinin
• Burns, Chemical (drug therapy, etiology, pathology)
• Drug Evaluation, Preclinical
• Epichlorohydrin
• Eye (drug effects, pathology)
• Eye Burns (chemically induced, drug therapy, pathology)
• Rabbits
• Time Factors
• Trypsin Inhibitors (therapeutic use)