[Treatment-effect on cyclosporin A-induced gingival hyperplasia in patients with organ transplantation: a longitudinal study].

Abstract

In the present study a newly developed concept for avoiding recurrences after the periodontal surgical treatment of cyclosporin A-induced gingival hyperplasia is described. Conventional gingivectomy results in restitutio per secundam, which promotes recurrences. To avoid this we tried to achieve a restitutio per primam by using a modified surgical technique. Ten patients, four treated under general anesthesia and six on an outpatient basis, were treated with this technique. Patients were monitored for 20 month. Pre- and postoperative care was performed in a standardized manner for all patients. During the surveillance, a long-term suppression of the cyclosporin-induced gingival hyperplasia could be found, but it was not possible to avoid recurrences totally.

• Authors: H Günay, B G Evers
• Journal: Parodontologie (Berlin, Germany) (Parodontol) Vol. 1 Issue 4 Pg. 329-42 (Nov 1990) ISSN: 0937-1532 [Print] Germany
• Vernacular Title: Behandlungseffekt auf Cyclosporin-A-induzierte Gingivahyperplasien bei organtransplantierten Patienten--Eine Verlaufskontrolle.
• PMID: 2100679 (Publication Type: English Abstract, Journal Article)

Chemical References

• Cyclosporins

Topics

• Adolescent
• Adult
• Child
• Cyclosporins (adverse effects)
• Female
• Gingival Hyperplasia (chemically induced, therapy)
• Humans
• Longitudinal Studies
• Male
• Middle Aged
• Organ Transplantation (adverse effects)